منابع مشابه
Pan-Vertebrate Toll-Like Receptors During Evolution
Human toll-like receptors (TLRs) recognize pathogen-associated molecular patterns (PAMPs) to raise innate immune responses. The human TLR family was discovered because of its sequence similarity to fruit fly (Drosophila) Toll, which is involved in an anti-fungal response. In this review, we focus on the origin of the vertebrate TLR family highlighted through functional and phylogenetic analyses...
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Inflamed tissue is often characterized by the production of NO and superoxide. These radicals react at diffusion-limited rates to form the powerful oxidant peroxynitrite (PN). When protonated, PN decomposes into either nitrate or reactive intermediates capable of mediating tissue damage by oxidation of protein, lipid, and nucleic acid. We recently have identified porphyrin derivatives capable o...
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A large number of research groups have proposed that chronic fatigue syndrome (CFS), fibromyalgia (FM), multiple chemical sensitivity (MCS) and, in some cases, posttraumatic stress disorder (PTSD) have multiple overlaps and may share a common etiology (cause). They have: • overlapping symptoms • many people are diagnosed as having more than one • cases of each are commonly initiated by a short ...
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35. Connern, C. P. and Halestrap, A. P. (1992) Biochem. J. 284,381-385 36. Kay, J. E., Moore, A. L., Doe, S. E. A., Benzie, C. R., Schonbrunner, R., Schmid, F. X. and Halestrap, A. P. (1 990) Transplant Proc. 22,96-99 37. Bergsma, D. J., Eder, C., Gross, M., Kersten, H., Sylvester, D., Appelbaum, E., Cusimano, D., Livi, G. P., McLaughlin, M. M., Kasyan, K., Porter, T. G., Silverman, C., Dunning...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2005
ISSN: 0008-6363
DOI: 10.1016/j.cardiores.2005.05.030